Outcome of Surgical and Radiotherapy Treatment of Medullobalstoma, (Our Experience in 15 Cases)

Authors

  • Muhammad Arshad Department of Neurosurgery, quaid-e-Azam Medical College (QAMC

Keywords:

Medulloblastoma, Radiotherapy, Chemotherapy, Posterior Fossa Syndrome

Abstract

Objective: To assess the efficacy of surgery and radiotherapy for the medulloblastoma.
Material and Methods: It is a study of fifteen (15) cases of Medulloblastoma operated at The Department of Neurosurgery Quaid-e-Azam Medical College / B.V. Hospital Bahawalpur. Study span is three years from January 2004 to December 2006 with follow up period of 5 years.
Results: Age range was 2 – 12 years with average age of 7 years. Eight (8) patients were male and seven (7) were female. In all patients surgery was performed. Radiotherapy (Craniospinal Axis) was given to all but two patients who expired before the initiation of radiotherapy, one patient died, two week after surgery and second patient, one month after surgery. Out of Thirteen (13) patients who were treated by surgery and radiotherapy, 4 died before 5 year of age (between 3 and5 year of age) and 9 patients were alive at 5 year follow up. So, our 3 year survival rate was 86.66% and 5 year survival rate was 60 %.Chemotherapy was not given to any patient. Mortality after surgery was 13.33%.
Conclusion: It is concluded that mainstay of treatment for medulloblastoma is surgery followed by radiotherapy to the whole craniospinal axis.

References

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Published

2018-09-30

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Original Articles