MVD as the First Line Therapy after Failed Medical Treatment; for Idiopathic Trigeminal Neuralgia

Authors

  • Attiq-ur- Rehman Department, of Neurosurgery Postgraduate Medical Institute Lahore General Hospital
  • ABDULLAH HAROON Department of Neurosurgery Unit – I
  • ASIF SHABBIR Department of Neurosurgery Unit – I
  • Abdul Majid Department of Neurosurgery Unit – I
  • Shahid Hameed Department of Neurosurgery Unit – I

Keywords:

Idiopathic trigeminal neuralgia, Microvascular decompression, Fascial Pain.

Abstract

Objective: To analyze the outcome of MVD as a first choice therapy when medical treatment has failed for the definitive management of Idiopathic Trigeminal Neuralgia.
Material and Methods:
Study was conducted at the Department of Neurosurgery PGMI / Lahore General Hospital, Lahore. This was a prospective observational case series from January 2007 to December 2008, 50 selected patients of Idiopathic Trigeminal Neuralgia diagnosed after radiological and clinical exclusion of secondary causes of Neuralgia presenting in whom medical management had failed were offered MVD as the first Intervention. All the patients were followed for one year post-operatively.
Results: Mean age was 59.2 years and minimum age 47 year and maximum 72 years. There was 16 males (32.0%) and females were 34 (68.0%). Male to female ratio was 1: 2.16. In 15 (30.0%) patients facial pain was on left side and 35 (70.0%) patients had right sided pain. V1 was found in 1 (2.0%) patient, V3 in 2 (4.0%) pati-ents, V1 and V2 in 2 (4.0%) patients, V1-3 in 17 (34.0%) patients, V2,3 in 28 (56.0%) patients. An Arterial loop was found in 37 (74.0%) patients as the compressing agent and a Vein only in 4 (8.0%) patients. Mixed artery and vein in 8 (16.0%) patients. Thick arachnoid was the compressing agent in 1 (2.0%) patient. Out of 50 patients 46 (92.0%) had Excellent outcome, 3 (6.0%) patients had Good outcome, 1 (2.0%) patient was in Fair outcome group. No patients were in Bad and Failure outcome groups.
Conclusion: Microvascular Decompression of trigeminal nerve is a safe and first choice therapy when medical treatment has failed for the definitive management of Idiopathic Trigeminal Neuralgia in otherwise medically fit patients provided Surgeon has adequate experience of performing the procedure.

References

1. Ashkan K, Marsh H: Microvascular decompression for trigeminal neuralgia in the elderly: a review of the safe-ty and efficacy. Neurosurgery 2004; 55: 840–850.
2. Barker FG II, Jannetta PJ, Bissonette DJ, Larkins MV, Jho HD: The long-term outcome of microvascular de-compression for trigeminal neuralgia. N Engl J Med 1996; 334: 1077–1083.
3. Javadpour M, Eldridge PR, Varma TR, Miles JB, Nur-mikko TJ: Microvascular decompression for trigeminal neuralgia in patients over 70 years of age. Neurology 2003; 60: 520.
4. Kondo A: Follow-up results of microvascular decom-pression in trigeminal neuralgia and hemifacial spasm. Neurosurgery 1997; 40: 46–52.
5. Sekula RF, Marchan EM, Fletcher LH, Casey KF, Jan-netta PJ: Microvascular decompression for trigeminal ne-uralgia in elderly patients. J Neurosurg 2008; 108: 689–691.
6. Sheehan J, Pan HC, Stroila M, Steiner L: Gamma knife surgery for trigeminal neuralgia: outcomes and progno-stic factors. J Neurosurg 2005; 102: 434–441.
7. Sindou M, Leston J, Howeidy T, Decullier E, Chapuis F: Microvascular decompression for primary Trigemi-nal Neuralgia (typical or atypical). Long – term effec-tiveness on pain; prospective study with survival ana-lysis in a consecutive series of 362 patients. Acta Neu-rochir (Wien) 2006; 148: 1235–1245.
8. Theodosopoulos PV, Marco E, Applebury C, Lamborn KR, Wilson CB: Predictive model for pain recurrence after posterior fossa surgery for trigeminal neuralgia. Arch Neurol 2002; 59: 1297–1302.
9. Rose FC. Trigeminal neuralgia. Arch Neurol 1999; 56: 1163-4.
10. Ameli NO. Avicenna and trigeminal neuralgia. J Neurol Sci 1965; 2: 105-7.
11. Coakham. The Surgical Treatment of Trigeminal Neu-ralgia. ACNR • Volume 7, Number 2 • May / June 2007.
12. Dandy WE. Concerning the cause of trigeminal neura-lgia. Am J Surg 1934; 24: 447–55.
13. Gardner WJ, Miklos MV. Response of trigeminal neu-ralgia to decompression of sensory root. Discussion of cause of trigeminal neuralgia. JAMA 1959; 170: 1773–6.
14. Jannetta PJ. Arterial compression of the trigeminal ner-ve at the pons in patients with trigeminal neuralgia. J Neurosurg 1967; 26: 159–62.
15. Adams CBT. Microvascular decompression: an alterna-tive view and hypothesis. J Neurosurg 1989; 57: 1–12.
16. Amjad S. Trigeminal neuralgia: analysis of pain distri-bution and Nerve involvement. Pakistan oral & dental journal Vol 28, No. 1; 2010.
17. Mumtaz Ali, Muhammad Pervez Khan, Abdul Aziz Khan, Zahid Khan. Idiopathic trigeminal neuralgia: cli-nical Presentations and operative findings on Microvas-cular decompression. JPMI 2009; Vol 23, No. 04: 322-325.
18. Riaz Ur Rehman, Azmatullah, Farooq Azam, Moham-mad Ilyas. Microvascular Decompression in Patients with Intractable Idiopathic Trigeminal Neuralgia. Jour-nal of Surgery Pakistan (International) 16 (1) January – March 2011.
19. Surgical Treatment of trigeminal neuralgia. Editorial. BMJ 1977: Vol 2: pt 6089.
20. Hakanson S. Trigeminal neuralgia treated by the injec-tion of glycerol into the trigeminal cystern. Neurosur-gery 1981; 9: 638-46.
21. Kalkanis SN, Eskander EN, Carter BS, Barker FG. Mi-crovascular decompression surgery in the United States, 1996 – 2000: mortality rates, morbidity rates and the effects of hospital and surgeon volumes. Neurosurgery 2003; 52: 1251-61.
22. Tatli, M.,Satici, O, Kanpolat, Y. Sindou, M. Various surgical modalities for trigeminal neuralgia: literature study of respective long – term outcomes. Acta Neuro-chirurgica , 2008; Volume: 150 Issue: 3; 243-55.
23. Pagni CA, Fariselli L, Zeme S. Trigeminal neuralgia. Non-invasive techniques versus microvascular decom-pression. It is really available any further improvement? Acta Neurochir Suppl. 2008; 101: 27-33.

Downloads

Published

2018-10-09

Issue

Section

Original Articles