To Determine the Frequency of Brain Abscess and its Common Bacteria in Patients Presenting with Highly Suspected Clinical Features

Authors

  • Naeem -ul-Haq Department of Neurosurgery, Lady Reading Hospital, Peshawar
  • Zahid Khan Department of Neurosurgery, Lady Reading Hospital, Peshawar
  • Seema Sharafat Department of Neurosurgery, Lady Reading Hospital, Peshawar
  • Muhammad Ishaq Department of Neurosurgery, Lady Reading Hospital, Peshawar

Keywords:

Frequency, Brain Abscess, bacteria, Viridians streptococci, Staphylococcus aureus

Abstract

Objective: To determine the frequency of brain abscess and its common bacteria in patients presenting with highly suspected clinical features.
Material and Methods: It was a Descriptive (cross sectional) Study conducted in the Department of Neur-osurgery Lady Reading Hospital Peshawar. Duration of study was 1 year, from Jan 2011 to Jan 2012. Total number of patients with highly suspected clinical features were 134. CT brain and MRI brain was done for these patients. SPSS version 17 was used for data analysis.
Results: Among 134 cases, 93 (63%) were male and 41 (3.60%) were female. Majority 49% (n = 66) were between 21 – 30 years of age. Frequency of brain abscess was revealed in 12.69% (n = 17), common bacteria was Streptococcus Viridians having 41.18% (n = 7) cases, Staphylococcus Aureus 29.41% (n = 5), Bacteriods fragilis was 17.65% (n = 3) and Peptostreptococcus 11.76% (n = 2).
Conclusion: The results of the study reveals frequency of brain abscess is still higher in our population while Viridians streptococci and Staphylococcus aureus are most common bacteria.

References

1. Ranjith K, Moorthy M, Rajshekhar M. Management of brain abscess. Neurosurg Focus, 2008; 24: 1-6.
2. Muzumdar D, Jhawar S, Goel A. Brain abscess. Int J Surg. 2010; 16: 1-9.
3. Carpenter J, Stapleton S, Holliman R. Retrospective analysis of 49 cases of brain abscess and review of the literature. Eur J Clin Microbiol Infect Dis. 2007; 26: 1-11.
4. Atiq M, Ahmad US, Allana SS, Chishti KN. Brain abs-cess in Children. Indian J Pediatr. 2006; 73: 401-4.
5. Parsad KN, Mishra AM, Gupta D, Husain N, Husain M, Gupta RK. Analysis of microbial etiology and mortality in patients with brain abscess. J Infect. 2006; 53: 221-7.
6. Martinez MO, Cabezudo JM, Portales IF, Perals LG, Sanchez JA, Yague LG. Pyogenic brain abscess. Neuro-cirugia (Astur), 2006; 17: 23-33.
7. Qasam M, Razaq MN, Saddiqe M, Iliyas M, Khattak A. Management of supratentorial brain abscess. JPMI,
2010; 24: 91-4.
8. Hakan T, Ceran N, Erdem I, Berkman MZ, Goktas. P. Bacterial brain abscesses. J Infect. 2006; 52: 359-66.
9. Tseng JH, Tseng MY. Brain abscess in 142 patients: factors influencing outcome and mortality. Surg Neurol. 2006; 65: 557-62.
10. Microbiology and management. J Child Neurol 1995; 10 (4): 283-8. Brook I. Brain abscess in children.
11. Goodkin HP, Harper MB, Pomeroy SL. Intracranial abscess in children: Historical trends at Children’s hos-pital, Boston. Pediatrics, 2004; 111 (8): 1765-70.
12. Piper C, Horstkotte B, Arendt G, Strauer BE. Brain abs-cess in children with cyanotic heart defects. Z Kardiol, 1994; 83 (3): 188-93.
13. Heilpern KL, Lorber B. Focal intracranial infections. Infect Dis Clin North Am. 1996; 10: 879-98.
14. H. LU, W.-N. CHANG, Y.-C. LIN. Bacterial brain abs-cess: microbiological features, epidemiological trends and therapeutic outcomes. Q J Med. 2002; 95: 501–509.

Published

201-03-30

Issue

Section

Original Articles