Analyzing the Rate of Complications after Endoscopic Transsphenoidal Surgery for Removal of Pituitary Adenomas

Khalid Khanzada, Ihsan ullah, Ali Haider

Abstract


Objective: Analyzing the rate of complications after endoscopic transsphenoidal surgery for removal of pituitary adenomas in neurosurgery department lady reading hospital Peshawar.
Materials and Methods: Retrospective study of 58 patients who underwent endoscopic transsphenoidal surgery for pituitary adenomas between July 2013 and June 2016. The Criteria for diagnosis of complications were clinical and radiological.
Results: 11 (18.96%) of the 58 patients who underwent endoscopic transsphenoidal surgery developed per-operative or postoperative complications most of which were managed successfully resulting in good outcome.
Conclusion: The rate of complications observed in our hospital are comparable to those in the international literature. There is a drop in the rate of complications with increasing experience of the neurosurgeon.
Abbreviations: Pts: Pituitary Tumors. TSS: Transsphenoidal Surgery. DI: Diabetes Insipidus. CSF: Cerebro-spinal Fluid. ICA: Internal Carotid Artery.

Full Text:

PDF

References


Colao A, Pivonello R, Di SC, Savastano S, Grasso LF, Lombardi G. Medical Therapy of pituitary adenomas: effects on tumor shrinkage. Rev Endocr Metab Disord. 2009; 10: 111–123.

Sheplan Olsen LJ, Robles IL, Chao ST, et al. Radiothe-rapy for prolactin secreting pituitary tumors. Pituitary, 2012; 15: 135–145.

Fatemi N, Dusick JR, de Paiva Neto MA, Kelly DF. The endonasal microscopic approach for pituitary ade-nomas and other parasellar tumors: a 10 – year expe-rience. Neurosurgery, 2008; 63 (4 suppl. 2): 244–256.

Cappabianca P, Cavallo LM, Colao A, et al. Endosco-pic endonasal transsphenoidal approach: outcome ana-lysis of 100 consecutive procedures. Minim Invasive Neurosurg. 2002; 45: 193–200.

Casler JD, Doolittle AM, Mair EA. Endoscopic surgery of the anterior skull base. Laryngoscope, 2005; 115: 16–24.

Charalampaki P, Ayyad A, Kockro RA, Perneczky A. Surgical complications after endoscopic transsphenoi-dal pituitary surgery. J Clin Neurosci. 2009; 16: 786–9.

D’Haens J, Van RK, Stadnik T, Haentjens P, Poppe K, Velkeniers B. Fully endoscopic transsphenoidal surgery for functioning pituitary adenomas: a retrospective comparison with traditional transsphenoidal micro-surgery in the same institution. Surg Neurol. 2009; 72: 336–340.

Dehdashti AR, Ganna A, Karabatsou K, Gentili F. Pure endoscopic endonasal approach for pituitary adenomas: early surgical results in 200 patients and comparison with previous microsurgical series. Neurosurgery 2008; 62: 1006–1015.

Cavallo LM, Cappabianca P, Galzio R, Iaconetta G, de Divitiis E, Tschabitscher M. Endoscopic transnasal approach to the cavernous sinus versus transcranial route: anatomic study. Neurosurgery, 2005; 56 (2 Suppl.): 379-89.

de Divitiis E, Cavallo LM, Esposito F, Stella L, Mes-sina A. Extended endoscopic transsphenoidal approach for tuberculum sellae meningiomas. Neurosurgery, 2007; 61 (5 Suppl.): 229-38.

Dehdashti AR, Gentili F. Current state of the art in the diagnosis and surgical treatment of Cushing disease: early experience with a purely endoscopic endonasal technique. Neurosurg Focus, 2007; 23: E9.

Frank G, Pasquini E, Farneti G, Mazzatenta D, Scia-rretta V,- Grasso V, et al. The endoscopic versus the traditional approach in pituitary surgery. Neuroendocri-nology, 2006; 83: 240-8.

de Divitiis E, Cappabianca P, Cavallo LM, Endoscopic transsphenoidal approach: adaptability of the procedure to different sellar lesions. Neurosurgery, 2002; 51 (3): p. 699-707.

Conceição Aparecida Dornelas; Tereza N. A. G. Nogu-eira; Evandro T. Alves; River A. B. Coêlho. Fatal com-plication after transsphenoidal surgery of pituitary ade-noma: case report. J Bras Patol Med Lab. June, 2015; V. 51, N. 3: p. 178-182.

Krzentowska-Korek A, Gołkowski F, Bałdys-Waligó-rska A, Hubalewska-Dydejczyk A. Ef"cacy and compli-cations of neurosurgical treatment of acromegaly. Pit-uitary, 2011; 14 (2): 157-62.

Santos AR, Fonseca Neto RM, Veiga JC, Viana Jr J, Scaliassi NM, Lancellotti CL, et al. Endoscopic endo-nasal transsphenoidal approach for pituitary adenomas: technical aspects and report of casuistic. Arq Neuropsi-quiatr. 2010; 68 (4): 608-12.

Armengot M, Gallego JM, Gómez MJ, Barcia JA, Bas-terra J, Barcia C. Transphenoidal endoscopic approa-ches for pituitary adenomas: a critical review of our ex-perience. Acta Otorrinolaringol Esp. 2011; 62 (1): 25-30.

Katznelson L, Atkinson JL, Cook DM, Ezzat SZ, Ham-rahian AH, Miller KK. American Association of Clini-cal Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Acrome-galy – 2011 update: executive summary. Endocr Pract. 2011; 17 (4): 636-46.

Cappabianca P, C.L., De Divitiis E, Endoscopic endo-nasal transsphenoidal surgery. Neurosurgery, 2004; 55 (4): p. 933-941.

Berker M, Hazer DB, Yucel T, et al. Complications of endoscopic surgery of the pituitary adenomas: analysis of 570 patients and review of the literature. Pituitary, 2012; 15: 288–300.

DeKlotz TR, Chia SH, Lu W, Makambi KH, Aulisi E, Deeb Z. Meta-analysis of endoscopic versus sublabial pituitary surgery. Laryngoscope, 2012; 122: 511–518.

Hadad G, Bassagasteguy L, Carrau RL, et al. A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap. Laryngoscope, 2006; 116: 1882–1886.

Kumar S, Darr A, Hobbs CG, Carlin WV. Endoscopic, endonasal, transsphenoidal hypophysectomy: retrospec-tive analysis of 171 procedures. J Laryngol Otol 2012; 126: 1033–1040.


Refbacks

  • There are currently no refbacks.
';