Epidemiology of Brain Abscess in Patients Presenting to Neurosurgery Department Lady Hospital Peshawar

Khalid Khanzada, Ihsan ullah, Muhammad Ishfaq


Objective: To know about epidemiology of brain abscess in patients presenting to neurosurgery department lady reading hospital Peshawar.
Material and Methods: This prospective observational study was conducted in Neurosurgery Department LRH Peshawar from 1st Jan 2011 – 30th Dec 2014 with total 3 year duration. All patients admitted with brain abscess were included in the study while patients of tuberculous meningitis, tuberculoma, glioblastoma multiformes, subdural empyema, extradural abscess were excluded. Patients age, gender, address, pre-operative signs and symptoms, cause of the abscess, site of the abscess, type of procedure performed for brain abscess drainage and amount of pus drained from abscess, Pre and post-operative complications with post-operative variation in clinical status were recorded on a designed Proforma from hospital charts and operation notes .Data was analyzed using SPSS version 20 and expressed in tables and charts.
Results: Out of 120 patients males were 70 (58.33%) while females were 50 (41.77%) with males to females ratio was 1.4;1 and majority of the patients were in the first three decades of life having frequency of 91 (75.77%) while mean age of presentation was 35.15 ± 2 SD. Regarding signs and symptoms nausea and vomiting were on top with 68 (56.66%) cases followed by fever in 56 (46.66%) patients while in signs meningism was commonest documented in 49 (40.83%) cases followed by the signs of raised intracranial pressure noted in 34 (28.34%) cases. Based on etiology, site of the brain abscess, type of procedure performed and amount of pus drained from abscess commonest etiology was otitus media in 43 (35.8%) cases, frontal lobe involvement was on the top in 37 (30.8% ),102 (85%) cases in 120 were treated by burr hole and aspiration and in 85(70.9%) up to 40 ml of pus was aspirated.
Conclusions: Brain abscess is common in young to middle age population due to unhygienic status of ears with males predominance. Frontal lobes of the brain is most common site of abscess formation and majority of the patients present with nausea, vomiting, fever, signs of raised intracranial pressure and meningism.
Key words: Brain abscess, Frontal lobes, Otitis media, Sign and symptoms of raised intracranial pressure and meningism.

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