Evaluation of Electrolyte Imbalance in Acute Stroke

  • Mukhtiar Ahmed Department of Neurosurgery, Medicine and Community Medicine Khairpur Medical College
  • Aziz ur Rehman DOW Medical University, Karachi, Pakistan
  • Safdar Ali Pervez
  • Farrukh Imtaiz Department of Neurosurgery, Medicine and Community Medicine Khairpur Medical College
  • Abdul Razaque
  • Khawar Anwar Punjab Institute of Neurosciences

Abstract

Objective:  Electrolyte imbalance is common in acute stroke; it may cause severe morbidity and mortality, so timely management of electrolyte imbalance may improve morbidity and mortality in cerebro-vascular accident. The purpose of this study was to evaluate electrolyte imbalance in acute stroke and its effect on the outcome of patients.

Material and Methods:  This study was prospective descriptive in nature and it is comprised of 106 patients of acute stroke after clinically diagnosis confirmed by CT scan brain plain admitted in Khairpur Medical College Hospital. Serum electrolyte along with the other baseline investigation was performed.

Results:  Hyponatremia was comparatively more common in brain infraction than spontaneous ICH. Hypokalemia is also more common in brain infarction as compared to the hemorrhagic stroke patients of this study.

Conclusion:  Incidence of Hyponatremia was more common than hypokalemia in patients with acute stroke.

Keywords:  Hemorrhage, Infraction, Hyponatremia, Hypokalemia.

References

1. Kalyan M, Nahdi WK, Kanitkar SA, Moharkar A, Saha R. Electrolyte Imbalance In Acute Stroke. National Journal of Integrated Research in
Medicine, 2017; 8 (4).
2. Smith W.S: Cerebrovascular diseases in: Harrison’s Principle of Internal Medicine.19th Ed, Mc-Graw Hill Companies; New York City, 2015: 2559.
3. Monica W. Project Investigators. The world Health Organization MONICA Project (monitoring trends and determinant in cardiovascular diseases). J Clin Epidemiol. 2008; 41 (2): 105-14.
4. World Health Organization. The top 10 causes of deaths. 2014. Available at:
http://www.who.int/mediacentre/factsheets/fs310/en/
5. Nemade ST, Patil MS, Chaudhari RA, Vankudre AJ. Serum electrolyte levels (sodium and potassium) in cerebrovascular accidents at a tertiary care hospital-a case control study. MVP Journal of Medical Science, 2016; 2 (1): 1-3.
6. Langhorne P, Stott DJ, Robertson et al. Medical complications after stroke: a multicenter study. Stroke, 2014; 31 (6): 1223-29.
7. WHO STEPS Stroke Manual: The WHO STEP wise approach to stroke surveillance. STEPS Stroke Surveil Man. 2016; 2 (1): 5-9.
8. Broderick J, Connolly S, Feldmann E, Hanley D, Kase C, Krieger D, Mayberg M, Morgenstern L, Ogilvy CS, Vespa P, Zuccarello M. REPRINT. Circulation, 2007; 116 (16): 391-413.
9. Stern RH. Severe symptomatic hyponatraemia. Treatment and outcome. A study of 64 cases. Ann Int Med. 2017; 107 (6): 656-64.
10. Coleman HA, Tare M, Tare M, Porkington HC. Endothelial potassium channels, endothelium-dependent hyperpolarisation and the regulation of vascular tone in health and disease. Clin Exp Pharmcol Physiol. 2014; 31 (9): 641e9.
Published
2020-12-25
Section
Original Article