Clinical Outcome of Microvascular Decompression In The Management Of Trigeminal Neuralgia In A Single Center: A Prospective Study
DOI:
https://doi.org/10.36552/pjns.v29i2.1054Abstract
Objectives: In the cases of trigeminal neuralgia unresponsive to medication or conservative measures, microvascular decompression is the preferred surgical technique. The objective of the current study was to evaluate the clinical outcomes of the microvascular decompression technique in the management of TN.
Material & Methods: This prospective, observational study spanned over two years from January 2021 to December 2022. Adults diagnosed with typical TN who were at least eighteen years old, and who were not responding to conservative treatment options, including carbamazepine and gabapentin, were enrolled in the study. The assessment of pain was performed using the Visual Analog Scale (VAS) and the Barrow Neurological Institute (BNI) pain intensity scale.
Results: The mean age of the patients was 52.4 ± 10.2 years, with a range from 32 to 74 years.
References
References:
Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018 Jan;38(1):1-211. doi: 10.1177/0333102417738202. PMID: 29368949.
Cole CD, Liu JK, Apfelbaum RI. Historical perspectives on the diagnosis and treatment of trigeminal neuralgia. Neurosurgical focus. 2005 May 1;18(5):1-0.
Cheshire Jr WP. Trigeminal neuralgia: diagnosis and treatment. Current neurology and neuroscience reports. 2005 Mar;5(2):79-85.
De Toledo IP, Réus JC, Fernandes M, Porporatti AL, Peres MA, Takaschima A, Linhares MN, Guerra E, Canto GD. Prevalence of trigeminal neuralgia: A systematic review. The Journal of the American Dental Association. 2016 Jul 1;147(7):570-6.
Katusic S, Beard CM, Bergstralth E, Kurland LT. Incidence and clinical features of trigeminal neuralgia, Rochester, Minnesota, 1945–1984. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society. 1990 Jan;27(1):89-95.
Wu J, Xiao Y, Chen B, Zhang R, Dai M, Zhang Y. Efficacy and safety of microvascular decompression versus percutaneous balloon compression in the treatment of trigeminal neuralgia: a systematic review and meta-analysis. Annals of Palliative Medicine. 2022 Apr;11(4):1391400-.
Bendtsen L, Zakrzewska JM, Abbott JA, Braschinsky M, Di Stefano G, Donnet A, Eide PK, Leal PR, Maarbjerg S, May A, Nurmikko T. European Academy of Neurology guideline on trigeminal neuralgia. European journal of neurology. 2019 Jun;26(6):831-49.
Di Stefano G, La Cesa S, Truini A, Cruccu G. Natural history and outcome of 200 outpatients with classical trigeminal neuralgia treated with carbamazepine or oxcarbazepine in a tertiary centre for neuropathic pain. The journal of headache and pain. 2014 Dec;15:1-5.
Bick SK, Eskandar EN. Surgical treatment of trigeminal neuralgia. Neurosurgery Clinics. 2017 Jul 1;28(3):429-38.
Patel SK, Markosian C, Choudhry OJ, Keller JT, Liu JK. The historical evolution of microvascular decompression for trigeminal neuralgia: from Dandy’s discovery to Jannetta’s legacy. Acta Neurochirurgica. 2020 Nov;162:2773-82.
Sandell T, Eide PK. Effect of microvascular decompression in trigeminal neuralgia patients with or without constant pain. Neurosurgery. 2008 Jul 1;63(1):93-100.
Sarsam Z, Garcia-Fiñana M, Nurmikko TJ, Varma TR, Eldridge P. The long-term outcome of microvascular decompression for trigeminal neuralgia. British journal of neurosurgery. 2010 Feb 1;24(1):18-25.
Andersen AS, Heinskou TB, Rochat P, Springborg JB, Noory N, Smilkov EA, Bendtsen L, Maarbjerg S. Microvascular decompression in trigeminal neuralgia-a prospective study of 115 patients. The Journal of Headache and Pain. 2022 Dec;23(1):145.
Reddy VK, Parker SL, Patrawala SA, Lockney DT, Su PF, Mericle RA. Microvascular decompression for classic trigeminal neuralgia: determination of minimum clinically important difference in pain improvement for patient reported outcomes. Neurosurgery. 2013 May 1;72(5):749-54.
Jagannath P, Venkataramana N, Bansal A, Ravichandra MJAjon. Outcome of microvascular decompression for trigeminal neuralgia using autologous muscle graft: a five-year prospective study. 2012;7(03):125-30.
Chakravarthi PS, Ghanta R, Kattimani V. Microvascular decompression treatment for trigeminal neuralgia. Journal of Craniofacial Surgery. 2011 May 1;22(3):894-8.
Bangash TH. Trigeminal neuralgia: frequency of occurrence in different nerve branches. Anesthesiology and pain medicine. 2011;1(2):70.
Hardy DG, Rhoton AL. Microsurgical relationships of the superior cerebellar artery and the trigeminal nerve. Journal of neurosurgery. 1978 Nov 1;49(5):669-78.
Tomasello F, Esposito F, Abbritti RV, Angileri FF, Conti A, Cardali SM, et al. Microvascular decompression for trigeminal neuralgia: technical refinement for complication avoidance. 2016;94:26-31.
La Torre D, Gorgoglione N, Cafarella D, Romano A, Lavano A, Germanò A, et al. A Novel Technical Refinement of Microvascular Decompression: Pain Relief and Complication Rate in a Consecutive Series of Patients With Trigeminal Neuralgia. 2020.
Mastronardi L, Caputi F, Cacciotti G, Scavo CG, Roperto R, Sufianov AJSNI. Microvascular decompression for typical trigeminal neuralgia: Personal experience with intraoperative neuromonitoring with level-specific-CE-Chirp® brainstem auditory evoked potentials in preventing possible hearing loss. 2020;11
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Copyright (c) 2025 Akram Ullah, Muhammad Ishfaq, Bakht Jehan , Muhamamad Younas, Muhammad Zubair , Abdul Haseeb SahibzadaThe work published by PJNS is licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Copyrights on any open access article published by Pakistan Journal of Neurological Surgery are retained by the author(s).
