Lateral Intraventricular Epidermoid Cyst: A rare case report
DOI:
https://doi.org/10.36552/pjns.v29i3.1069Abstract
Abstract:
Epidermoid cysts originate from ectopic embryonic epithelial cells and are a very common type of benign intracranial tumor. However, the incidence of intraventricular epidermoid cysts is low, and lateral intraventricular epidermoid cysts are even rarer. Here, we present a case of lateral intraventricular epidermoid cyst and review the relevant literature. A 33?year?old male who was presented with complaints of aphasia, vomiting, inability to walk and previous history VP shunt which was blocked on examination. A computed tomography of the brain showed a low?density mass in the lateral ventricle and enlargement of the left ventricle. Cranial magnetic resonance imaging further confirmed that the mass was an epidermoid cyst. The patient underwent microscopic surgical resection combined with endoscopy via the Keen’s point as a tract to reach the ventricle. The mass was satisfactorily removed, and the patient recovered well. Lateral intraventricular epidermoid cysts often present with clinical symptoms due to the invasion of surrounding brain tissue or blockage of the cerebrospinal fluid system. Diagnosis relies on examination by magnetic resonance imaging, and treatment relies on surgical resection. The prognoses of patients are mostly excellent and depend on whether the tumor is resected cleanly or not.
Key Words:
Epidermoid cyst, lateral intraventricular, prognosis, surgery
References
Zhou LF. Intracranial epidermoid tumours: Thirty-seven years of diagnosis and treatment. British Journal of Neurosurgery [Internet]. 1990 Jan [cited 2025 Feb 7];4(3):211–6. Available from: http://www.tandfonline.com/doi/full/10.3109/02688699008992726
Zhou F, Yang Z, Zhu W, Chen L, Song J, Quan K, et al. Epidermoid cysts of the cavernous sinus: clinical features, surgical outcomes, and literature review. Journal of Neurosurgery [Internet]. 2017 [cited 2025 Feb 7];129(4):973–83. Available from: https://thejns.org/view/journals/j-neurosurg/129/4/article-p973.xml
Yanamadala V, Lin N, Walcott BP, Baird LC, Smith ER. Spontaneous regression of an epidermoid cyst of the cavernous sinus. Journal of Clinical Neuroscience [Internet]. 2014 [cited 2025 Feb 7];21(8):1433–5. Available from: https://www.sciencedirect.com/science/article/pii/S0967586814001507
Li F, Zhu S, Liu Y, Chen G, Chi L, Qu F. Hyperdense intracranial epidermoid cysts: a study of 15 cases. Acta Neurochir (Wien) [Internet]. 2007 Jan 14 [cited 2025 Feb 7];149(1):31–9. Available from: http://link.springer.com/10.1007/s00701-006-1060-6
Dufour H, Fuentes S, Metellus P, Grisoli F. Intracavernous epidermoid cyst. Case report and review of the literature. Neuro-chirurgie [Internet]. 2001 [cited 2025 Feb 7];47(1):55–9. Available from: https://europepmc.org/article/med/11283457
Pamir MN, Kilic T, Özek MM, Özduman K, Türe U. Non-meningeal tumours of the cavernous sinus: a surgical analysis. Journal of Clinical Neuroscience [Internet]. 2006 [cited 2025 Feb 7];13(6):626–35. Available from: https://www.sciencedirect.com/science/article/pii/S0967586806002621
Farhoud A, Khedr W, Aboul-Enein H. Surgical Resection of Cerebellopontine Epidermoid Cysts: Limitations and Outcome. J Neurol Surg B [Internet]. 2018 Apr [cited 2025 Feb 7];79(02):167–72. Available from: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1606220
Höhne J, Brawanski A, Schebesch KM. Retrosigmoid Craniotomy for Cerebellopontine Epidermoid Cyst. J Neurol Surg B [Internet]. 2019 Jun [cited 2025 Feb 7];80(S 03):S329–S329. Available from: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1677844
de Araujo Paz D, da Costa MDS, Rodrigues TP, Riechelmann GS, Suriano ÍC, Zymberg ST. Endoscopic treatment of a third ventricular epidermoid cyst. World Neurosurgery [Internet]. 2017 [cited 2025 Feb 7];99:813-e7. Available from: https://www.sciencedirect.com/science/article/pii/S1878875016313109
Pojski? M, Arnautovi? KI. Microsurgical Resection of the Epidermoid Tumor in the Cerebellopontine Angle. J Neurol Surg B [Internet]. 2019 Jun [cited 2025 Feb 7];80(S 03):S327–8. Available from: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1677499
Koot RW, Jagtap AP, Akkerman EM, Den Heeten GJ, Majoie CB. Epidermoid of the lateral ventricle: evaluation with diffusion-weighted and diffusion tensor imaging. Clinical neurology and neurosurgery [Internet]. 2003 [cited 2025 Feb 7];105(4):270–3. Available from: https://www.sciencedirect.com/science/article/pii/S0303846703000295
Aher RB, Singh D, Singh H, Saran RK. Lateral intraventricular epidermoid in a child with hydrocephalus. Journal of Pediatric Neurosciences [Internet]. 2012 [cited 2025 Feb 7];7(3):205–7. Available from: https://journals.lww.com/jopn/fulltext/2012/07030/lateral_intraventricular_epidermoid_in_a_child.14.aspx
Bhatoe HS, Mukherji JD, Dutta V. Epidermoid tumour of the lateral ventricle. Acta Neurochir (Wien) [Internet]. 2006 Mar [cited 2025 Feb 7];148(3):339–42. Available from: http://link.springer.com/10.1007/s00701-005-0678-0
Kashyap S, Cheema B, Chhabra V. Endoscopic resection of the third ventricular epidermoid cysts: A case review and review of literature. Surgical Neurology International [Internet]. 2019 [cited 2025 Feb 7];10. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744775/
Rubino F, Aguilera S, Campbell JI, Mural M, Salas E, Cersosimo TA. Purely endoscopic supracerebellar infratentorial approach for epidermoid cyst in third ventricle. Surgical Neurology International [Internet]. 2019 [cited 2025 Feb 7];10(Suppl 1):S21–5. Available from: https://europepmc.org/article/pmc/7159061
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Copyright (c) 2025 Faiqa Filza Khan, Sohail Daud Khan, Ahmad Reshad Payenda, Hazrat Nabi, Mohammad Naseem AfghanThe work published by PJNS is licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Copyrights on any open access article published by Pakistan Journal of Neurological Surgery are retained by the author(s).
