Extent of Resection and Complications in Transsphenoidal Surgery for Pituitary Adenoma and Its Outcome

Abstract

Objective:  The aim of the research is to determine the level of resection and postoperative complications during transsphenoidal surgery in pituitary adenoma.

Materials & Methods:  Seventy patients with radiologically confirmed pituitary adenomas who met the inclusion criteria were included in the final analysis. An expert neurosurgeon carried out all the procedures. The degree of tumor resection was evaluated based on comparing preoperative to the postoperative magnetic resonance imaging (MRI) scans at three months postop and ranged from gross total, near total, and subtotal resection. The postop complications were also evaluated, including CSF leak, hematoma, diabetes insipidus, and hyponatremia.

Results:  The average age of the participants in the study was 48.01, and the standard deviation was 11.13, with most of the patients being males (65.7 percent). Gross total resection was attained in 57.1%, and near-total and subtotal resection were attained in 15.7% and 27.1% cases, respectively. In relation to the complications,
CSF leak had a case of 10.0 percent, diabetes insipidus cases were 5.7 percent, and 8.6 percent cases had hyponatremia.

Conclusion:  Transsphenoidal surgery for pituitary adenoma demonstrated grand total resection in 57.1% of cases, near total resection in 15.7%, and subtotal resection in 27.1% of cases. CSF leak was the most frequent post-op complication.