Role of Topical Usage of Vancomycin Powder in Prevention of Wound Infection in Spinal Surgery


  • Muhammad Ajmal Khan Department of Neurosurgery Unit – II Lahore General Hospital,
  • RIZWAN SHARIF Department of Neurosurgery, 1Lahore General Hospital
  • MUZAMMIL IRSHAD Nishtar Medical College, Multan


Spinal surgery,, Topical application, Vancomycin, Wound infection


Objective: To determine the efficacy of topical usage of vancomycin powder at wound site to prevent wound infection in spinal surgery.
Material and Methods: A prospective study of 62 patients during a period of 6 months with follow-up of 2 weeks post-operatively was performed at Lahore General Hospital Lahore. Patients were divided into two groups: group A and group B, each containing equal numbers of patients. In group A, only prophylactic intravenous antibiotics were used for 5 days. In group B intravenous antibiotics along with topical Vancomycin powder were used at operative site in spinal surgery.
Results: During period of follow-up in 2 weeks post-operatively, incidence of wound infection in group A patients was 6.42% in comparison to Group B patients which was 2.4%. No adverse effects were documented by direct usage of Vancomycin powder at wound site.
Conclusion: Topical usage of Vancomycin powder at wound site reduces infection rate significantly in spinal surgery.


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