MRI Guided Stereotactic Biopsies or Aspirations in Deep Seated Brain Lesions: An Experience of 146 Cases at Nishtar Hospital, Multan

Authors

  • Amir Dawood Dawood Neurosurgery Nishtar Medical College,
  • ZAHID HUSSAIN Department of Neurosurgery Nishtar Medical College and Hospital
  • SHOAIB SALEEM Department of Neurosurgery Nishtar Medical College and Hospital
  • Muhammad Azhar Javed Department of Neurosurgery Nishtar Medical College

Keywords:

Stereotactic technique,, brains, cyst, MRI guided interventional procedures

Abstract

Objective: To determine frequency of positive biopsies or aspirates and safety in deep seated brain lesion, with use of Magnetic Resonance Imaging compatible stereotactic system.
Study Design: Prospective cross sectional.
Setting: The study was performed at Neurosurgery Department Nishtar Hospital, Multan.
Duration of Study: From 01-07-2008 to 30-06-2012.
Material and Methods: A total of 146 patients of age between 12 – 18 years of either sex having deep, intrinsic cystic lesion of the brain less or equal to 4 cm2 in size and excluding the extensively vascular lesion diagnosed on Computed Tomography and Magnetic Resonance Imaging underwent Stereotactic biopsy or aspiration with Mag-netic Resonance Imaging compatible Leksell’s stereotactic system. The tissue specimens were analyzed by stan-dard histopathological methods. The safety was measured in context of absence of complications i.e. hemorrhage, new onset of neurological deficit and fits. Data was analyzed via computer software SPSS 10 version for win-dows.
Results: Among 146 patients with deep seated cystic brain lesions were selected for aspiration by using MRI guided stereotactic system. Their age ranged from 12 years to 80 years with Mean = 37.73 ± Standard deviation (SD) = 18.12. Among them 86 (58.9%) were male and 60 (41.1%) female. Biopsies or aspirates were positive in 136 (93.2%) cases while negative in 10 (6.8%) cases.
Conclusion: We conclude that MRI assisted stereotactic brain aspiration is safe and effective procedure with a high diagnostic yield at our center.

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Published

2018-10-09

Issue

Vol. 16 No. 2 (2012): July-December

Section

Original Articles

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