Early Postoperative Complications of Endoscopic Endonasal Transsphenoidal Surgery for Resection of Pituitary Adenoma
Objectives: To determine early postoperative complications of endoscopic endonasal transsphenoidal surgery for resection of pituitary adenoma.
Materials and Methods: This Descriptive Case Series was carried out at the Department of Neurosurgery, Lady Reading Hospital, MTI, Peshawar. 124 patients of either gender between the age of 16 – 60 were already diagnosed with cases of pituitary adenoma. Patients included in this study were surgically treated by Endoscopic endonasal transsphenoidal surgery. Patients were followed up for seven days after surgery and assessed for CSF leak, the incidence of diabetes insipidus epistaxis, and meningitis. Stratification was done for age and gender and p-value < 0.05 (chi-square).
Results: CSF leak was observed in 2.4% (n = 3) of patients, diabetes insipidus was found in 11.3% (n = 14), Epistaxis in 1.6% (n = 2), and meningitis in 1.6% (n = 2) patients. No statistically substantial difference for both postoperative complications was observed based on gender and age-based stratification.
Conclusion: Diabetes insipidus was a common early postoperative problem that was found in 11.3% of patients, CSF leak was found in 2.4%, epistaxis in 1.6% while meningitis in 1.6% of the cases following Endoscopic endonasal transsphenoidal surgery for pituitary adenomas. Though, there was not any statistically significant association found among different age groups and genders for complications studied.
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