Awake Craniotomy Versus Surgery Under General Anaesthesia for Resection of Brain Tumour; A Systematic Review of Randomized Control Trials
DOI:
https://doi.org/10.36552/pjns.v28i2.923Abstract
Objectives: To evaluate the clinical evidence on the comparison of results between an awake craniotomy and general anesthesia surgery for brain tumor removal.
Materials & Methods: A systematic literature search was carried out using the PubMed, Cochrane Library, EMBASE, and MEDLINE databases using key terms such as awake craniotomy, awake brain surgery, awake craniotomy, anesthesia craniotomy, asleep craniotomy, asleep brain surgery, and general anesthesia. The PICO (Participant, Intervention, Comparison, and Outcome) approach was used to extract the studies contrasting the impact of awake craniotomy versus general anesthesia on outcomes included in this systematic review. PRISMA guidelines were followed throughout.
Results: 102 records were identified out of which 8 were included in the final qualitative synthesis (2 RCTs, Cohort). All reported neurological impairments in both groups, except 2. Six studies indicated early language abnormalities and early motor deficiencies. Six studies indicated early language abnormalities and early motor deficiencies. The mean operation time of the General Anesthesia group was more than that of Awake Craniotomy. Awake craniotomy surgery was associated with an average reduction of 4 to 8 days in the hospital.
Conclusion: Under GA, AC (add abbreviations of these) offers a workable substitute for craniotomy for individuals with gliomas penetrating expressive areas; awake craniotomy with electrical stimulation is linked to improved long-term neurological and language abilities as well as a shorter hospital stay.
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Copyright (c) 2024 Mahboob Khan, Abdul Hameed Khan, Farooq Sherzada, Abdul Basit Khan, Laila Ghaffar, Nayyab OrakzaiThe work published by PJNS is licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Copyrights on any open access article published by Pakistan Journal of Neurological Surgery are retained by the author(s).
