Comprehensive Analysis of Spinal Dysraphism: Early Institutional Experience at Pediatric Neurosurgery of Punjab Institute of Neurosciences
DOI:
https://doi.org/10.36552/pjns.v28i2.951Keywords:
Keywords: Spinal Dysraphism, Pediatric Patients, Clinical Presentations, Cutaneous FindingsAbstract
Objective: To examine the demographic and clinical characteristics of pediatric patients presenting with spinal dysraphism.
Material and Methods: This retrospective study was conducted at the Department of Pediatric Neurosurgery, Punjab Institute of Neurosciences in Lahore and included data from patients aged <16 years with spinal dysraphism over 7 months from March 2023 to September 2023. Data analysis was performed using SPSS version 27.0.
Results: Among 32 patients, age distribution: <1 year (37.5%, mean age: 5.58±2.31 months), 1-4 years (25%, mean age: 3.25±0.6 years), 5-15 years (37.5%, mean age: 11±2.6 years). Gender: 22 males (68.75%), 10 females (31.25%). The most prevalent clinical presentations were Myelomeningocele (18.75%) and Meningocele (15.63%), both predominantly observed in patients under 1 year of age. Among the cutaneous findings, Fluid sacs (34.38%) and Tuft of Hair (15.63%) were the most common. In terms of other clinical findings, Lower Limb Weakness (50.00%) and Lower Limb Muscle Atrophy (21.88%) had the highest percentages.
Conclusion: The study revealed a diverse age distribution, with Myelomeningocele and Meningocele being common clinical presentations, especially in infants. Some of the physical signs of the condition included a fluid sac. a tuft of hair on the back, and weak and underdeveloped leg muscles.
References
REFERENCES
Eagles ME, Gupta N. Embryology of spinal dysraphism and its relationship to surgical treatment. Can J Neurol Sci. 2020;47(6):736-46.
Le HK, Cardona-Grau D, Chiang G. Evaluation and long-term management of neurogenic bladder in spinal dysraphism. Neoreviews. 2019;20(12):e711-e24.
Reghunath A, Ghasi RG, Aggarwal A. Unveiling the tale of the tail: An illustration of spinal dysraphisms. Neurosurg Rev. 2021;44(1):97-114.
AMIR S, KHAN MN, KHAN I, AFRIDI A, AMAN A. Pattern of presentation of spinal dysraphism: A study of 72 patients in hayatabad medical complex peshawar, pakistan. Pakistan Journal Of Neurological Surgery. 2020;24(3):277–82-–82.
Copp AJ, Stanier P, Greene ND. Genetic basis of neural tube defects. Textbook of pediatric neurosurgery. 2020:2275-94.
Ayyangar R, Bowman A. Myelomeningocele and other spinal dysraphisms. Braddom's physical medicine and rehabilitation: Elsevier; 2021. p. 1027-48. e6.
Vetrano IG, Barbotti A, Erbetta A, Mariani S, Bova SM, Colombo L, et al. Multidisciplinary management of children with occult spinal dysraphism: A comprehensive journey from birth to adulthood. Children (Basel). 2022;9(10):1546.
Gohar R, Rehman L, Bokhari I, Ahmed T, Ahmed S, Mumtaz D. Incidence of post-operative cerebrospinal fluid leak in patients operated for spinal dysraphism. Pakistan Journal Of Neurological Surgery. 2023;27(2):187-92.
Khan M, Hussain A, Gul H, Syed A. Spectrum of spinal dysraphism in pediatric patients in a tertiary care hospital. Pakistan Journal Of Neurological Surgery. 2021;25(2):225-36.
Gupta VK, Bhat A, Sharma S, Gupta B. Spinal dysraphism: Presentation, management and outcome of patients undergoing surgery. International Journal of Innovative Research in Medical Science (IJIRMS). 2021;6(08).
Rehmani A, Qazi SMY. Pathological patterns and clinical presentations of spinal dysraphism in different age groups. Annals of Punjab Medical College (APMC). 2021;15(4):250-4.
Taj FT. Cutaneous markers of spinal dysraphism: A cross sectional study. Indian Journal of Paediatric Dermatology. 2018;19(3):215-9.
Choi SJ, Yoon HM, Hwang JS, Suh CH, Jung AY, Cho YA, Lee JS. Incidence of occult spinal dysraphism among infants with cutaneous stigmata and proportion managed with neurosurgery: A systematic review and meta-analysis. JAMA network open. 2020;3(7):e207221-e.
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Copyright (c) 2024 Hassaan Zahid, Muhammad Irfan, Usman Ahmad Kamboh, Asad Iftikhar Shah, Hassan Ali, Syed Shahzad HussainThe work published by PJNS is licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Copyrights on any open access article published by Pakistan Journal of Neurological Surgery are retained by the author(s).