Evaluating Mean Platelet Volume as an Independent Risk Factor for Stroke

Authors

  • Syed Farhan Uddin Department of Physiology, Muhammad Medical College, Mirpurkhas
  • Habib-ur-Rehman Chohan Department of Physiology, Muhammad Medical College, Mirpurkhas, Pakistan.
  • Shafaq Ansari Department of Physiology, Muhammad Medical College, Mirpurkhas
  • Naila Noor Department of Physiology, Muhammad Medical College, Mirpurkhas, Pakistan
  • Ahmed Hussain Suhag Department of Physiology, Muhammad Medical College, Mirpurkhas, Pakistan.
  • Kiran Waheed Department of Biochemistry, LIMHS,THATTA Pakistan

DOI:

https://doi.org/10.36552/pjns.v28i3.991

Keywords:

Stroke, Mean Platelet Volume, System XN 3000, intracranial hemorrhage.

Abstract

Objective:  The study aimed to evaluate the effects of mean platelet volume on stroke.

Materials & Methods:  A cross-sectional study was conducted at Muhammad Medical College, Mirpurkhas, Pakistan. The sample size of this study was 200 participants including 50 stroke patients and 150 controls. Participants were aged 40-80 years, with a baseline NIHSS score of ? 5. Blood samples (5 ml) were collected and analyzed for mean platelet volume (MPV). Blood pressure was measured manually.

Results:  The results show that individuals with raised MPV have a higher incidence of stroke than individuals with normal MPV. The Chi-Square test revealed a significant association between elevated MPV and stroke incidence (p = 0.0001). The demographic data showed that the stroke group had a higher mean age (59.32±8.14 years) compared to the control group (52.19±12.30 years), with a significant p-value of 0.0002. Systolic and diastolic blood pressures were significantly higher in the stroke group (p < 0.05). MPV was significantly elevated in stroke patients (11.94±0.65 fL) compared to controls (7.90±0.83 fL), with a p-value of 0.0001.

Conclusion:  There is a significant relationship between raised MPV in patients with stroke compared to the normal population.

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Published

2024-09-01

Issue

Vol. 28 No. 3 (2024): July-September

Section

Original Articles

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Copyright (c) 2024 PROF. DR SYED FARHAN Dr syed farhan, . Dr. Habib-ur-Rehman Chohan . Dr. Habib-ur-Rehman Chohan, Dr Naila Noor Dr Naila Noor, Dr. Shafaq Dr. Shafaq, Dr Ahmed Hussain Suhag , Dr Ahmed Hussain Suhag, Dr Kiran Waheed Dr Kiran Waheed

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