The Surgical Management of Supratentorial Astrocytomas Study of Preoperative Functional Status and Grade of Tumour For The Final Outcome
Keywords:
Supratentorial astrocytoma, urgical morbidityAbstract
Objective: Thirty cases of supratentorial extraganglionic astrocytoma were studied pre-and post operatively to evaluate the surgical Mortality and morbidity in relation to preoperative Karnofskys performance scale and histopathology of astrocytoma study. Comparative observational study conducted Neurosurgery Unit II, PGMI / Lahore General Hospital, Lahore.
Results: Mortality was 26.6% (8 patients), 87.5% patients having KPS <70 and 12.5% patients having KPS >70, as the level of significance is 0.1, p. value is 0.14. Mortality was high in high grade astrocytoma; G IV 50%, G III 37.5% and low in low grade astrocytoma; G II- 12.5% and G I-0%. With 0.1 level of significance, p. value is 0.07. Surgical morbidity was 50% (15 patients), of which 60% was early morbidity. Delayed morbidity occurred in 13% and was mixed (early and delayed) in 27%. Morbidity was high in high grade astrocytomas; G IV 27% G III - 47% and low in low grade astrocytoma G II 26% and G I-0%.
Conclusion: Mortality depended upon pre operative functional status and histopathological grade of astrocytoma in this study. Quality of life after surgical excision also depended upon the pre operative neurological status.
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